This would substantively reduce childrens incidental exposure to tobacco products at convenience stores and gas stations, and adolescents access to them, without increasing incentives to choose more lethal combustible products over non-combustible options like e-cigarettes. This work was supported by a grant from the National Institute on Drug Abuse of the National Institutes of Health and FDA Center for Tobacco Products (CTP)
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To investigate this putative lineage relationship, we targeted the POU2F3 and FOXI1 TF genes, required for tuft cell 19 and ionocyte specification, respectively 17,19 , using CRISPR/Cas9 KO in human tracheal basal cells ( n = 5 donors, Supplementary Fig